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Repeated IVF Failures-Management

September 14, 2024

Couples who struggle to conceive on their own due to fertility issues opt for IVF treatment. IVF is the latest technique for successful conception for couples with fertility problems. You cannot expect success in the first IVF cycle. Your fertility specialist suggests going for multiple IVF cycles to increase the chance of conception. But it is quite disheartening for couples to face multiple IVF failures. Here is a detailed outlook on IVF failure management for couples facing repeated IVF failure.

Book an online appointment with Dr. Meenu Handa for Pregnancy, Gynecology, fertility & IVF related issues.

What is Repeated IVF Failure?

IVF is a process where the eggs and the sperm are collected and allowed for fertilisation in a controlled environment. The healthy embryo is selected and transferred to the uterus. On successful implantation, the embryo grows into a fetus. This procedure can fail, resulting in IVF failure. Repeated failure of the process is called repeated IVF failure. It is a condition where you fail to conceive even after several IVF attempts with healthy embryos.

Causes of Repeated IVF Failure

It is difficult to figure out the exact cause of repeated IVF failure. Various factors are responsible for multiple IVF failures, including age, egg and sperm quality, lifestyle, and prevailing health conditions. Multiple IVF failure is attributed to a variety of causes.

Poor Quality of Eggs and Sperm: The quality of eggs and sperm deteriorates as the couple ages. The success rate of IVF is less for women over the age of 35 due to poor egg quality. Men over 40 produce poor-quality sperm.

Unhealthy Embryos: This is the main reason for failed IVF. This is indirectly related to poor quality eggs and sperms. When average quality embryos or unviable embryos are used during the IVF process, the implantation fails, resulting in IVF failure.

Chromosomal Abnormal Embryos: The use of chromosomal abnormal embryos can also be the cause of IVF failure. This is common in women in their mid-30s and men in their 40s.

Autoimmune Disorders: Women who suffer from an autoimmune disorder undergo repeated IVF failure as the disease inhibits implantation of the embryo. Many women tend to produce antibodies that can impair embryos implantation.

Uterine Issues: Women who suffer from uterine health disorders like fallopian blocks endometriosis. Fibroids and others have less chance of success in IVF treatment.

Improper Lifestyle: The success of your IVF cycle is closely related to your lifestyle. Smoking, drinking, poor eating habits, and obesity increase the risk of IVF failure. Sedentary life style and overall stress and anxiety also contribute to unhealthy microenvironment that impairs implantation.

Managing Your Grief

It is devastating for couples to undergo repeated IVF failures. They feel all their efforts have gone in vain. They lose hope and are left with a feeling of numbness. Understanding the situation can help you let go of your grief and cope with the situation. Multiple IVF failure grief may also result in depression in couples. IVF failure recovery is important for couples facing repeated IVF failure. Here are ways to manage your grief due to repeated IVF failure.

  • Take A Break: Stop all fertility treatments for a month or more. This helps you relax your mind and body.
  • Give Time to Heal: You must give your mind and body time to heal. It is ok to feel upset. Express your grief by writing or talking with your loved one. This can help let go of the grief.
  • Go for Professional Counselling: An open talk with a professional counsellor can help you manage your stress due to repeated IVF cycles. Share your feelings and emotions with your therapists, who offer the right advice based on your mental health.
  • Practice Relaxation Techniques: Calm your mind with deep breathing, meditation, and yoga. These techniques help greatly alleviate stress.
  • Join Support Groups: Connect with people who have undergone IVF failures. Their real-life experiences can help you cope with the loss.
  • Prioritise Self-Care -Taking care of your health is important for your well-being. Self-care activities like spending time outdoors, getting pedicures, reading books, etc., can relax your body and mind.

Exploring Alternatives for IVF

Couples who face repeated IVF cycle failures need not lose hope, as there are a lot of options to help them conceive. A fertility specialist can help you choose the proper treatment based on the cause of the IVF failure.

IVF: You can try for another IVF cycle after treating the exact cause of IVF failure. When the cause of IVF failure is assessed, the success rate of IVF cycles may increase. Performing genetic embryo testing before implantation can help improve the success rate of IVF procedures.

Laparoscopy: Performing laparoscopy procedures to treat the underlying fertility issues can maximise the success of further IVF cycles.

Uterine and Ovarian Rejuvenation: In this fertility treatment, the endometrium receptivity can be optimized by various techniques like ERA. The fertility specialist administers medications to improve the egg quality and blood platelet count.

Egg Freezing: Women with multiple IVF failures can freeze their eggs so that they can be used for future fertility treatments. This is a great option for women over 35 years and men over 40 years, as the egg and sperm quality deteriorate as you age.

Genetic Testing: Couples facing multiple IVF failures can opt for genetic testing to examine if the genetic factor is the cause of IVF failure.

Opt for Donor Eggs or Sperm: If the exact cause of IVF failure is the poor quality of egg or sperm, then try using donor eggs or sperm for your IVF treatment.

Practicing a Healthy Lifestyle: Couples can conceive independently when they adapt to a healthy lifestyle. Eating a balanced and nutritious diet can keep their bodies healthy, and regular exercise keeps them fit.

Conclusion

It is challenging for couples to undergo repeated IVF failure. Consult an experienced fertility specialist to assess the actual cause of IVF failure. Couples who face repeated IVF failure must never lose hope. There are plenty of other fertility treatments that help couples to enter parenthood.

FAQs

1. How can we evaluate the cause of repeated IVF failures?

The following helps to evaluate the cause of repeated IVF failures

  • Preimplantation genetic testing is done to assess the embryos for chromosomal abnormalities.
  • Uterine evaluation to assess your uterine health.
  • Sperm DNA fragmentation test to check the quality of DNA in the sperm.
  • Endometrial Receptivity Assay for optimizing implantation window.

2. When should we consider using donor eggs or donor sperm?

  • You can consider using donor eggs or donor sperm when you face multiple IVF failures due to poor egg quality or sperm.

3. What are some common reasons for repeated IVF failures?

  • Uterine abnormalities
  • Poor quality embryos
  • Poor quality of eggs and sperm
  • Chromosomal abnormalities of the embryo
  • Elderly aged couples

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